SEDATION SHOWDOWN: BARBITURATES VS. BENZODIAZEPINES │ EP117

In this episode, we’re covering barbiturates and benzodiazepines, two drug classes that both act at the GABA-A receptor but have important differences in their pharmacology, clinical effects, and reversal.

In this episode:

How barbiturates and benzodiazepines modify the GABA-A receptorWhy barbiturates increase chlo ride channel duration while benzodiazepines increase frequencyMethohexital, thiopental, midazolam, diazepam, and lorazepamKey pharmacokinetic and clinical differences between the major drugsFlumazenil reversal and the board-relevant risks you need to remember

This episode is part of our 12-week SEE/NCE podcast series, designed to follow the Atomic Anesthesia SEE/NCE Study Plan week by week.

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Mentioned in this episode:

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