
← Dr RR Baliga's "Got Knowledge Doc" Podkast24. Okt. · 2 Min.
🧬 Don't Block It—Destroy It! The Protein Degrader Revolution
🧬 Don't Block It—Destroy It! The Protein Degrader Revolution
🧬 Don't Block It—Destroy It! The Protein Degrader Revolution
💊 What if we could eliminate disease-causing proteins instead of merely blocking them?
🔬 Meet PROTACs and molecular glues—innovative drugs that harness the cell's recycling machinery to destroy troublesome proteins.
📊 In multiple myeloma, a molecular-glue-based combination achieved 42 vs. 20 months of progression-free survival.
💰 With ~200 degraders in development and over $5 billion in deals, the pharmaceutical industry is betting big!
⚠️ The challenge? Avoiding destruction of healthy proteins.
🎙️ Dr RR Baliga's Podkast for the Kurious Doc
Where Curiosity Meets Clarity!
#PrecisionMedicine #Oncology #DrugDiscovery