Dr RR Baliga's "Got Knowledge Doc" Podkast

← Dr RR Baliga's "Got Knowledge Doc" Podkast24. Okt. · 2 Min.

🧬 Don't Block It—Destroy It! The Protein Degrader Revolution

🧬 Don't Block It—Destroy It! The Protein Degrader Revolution24. Okt.2 Min.

🧬 Don't Block It—Destroy It! The Protein Degrader Revolution

💊 What if we could eliminate disease-causing proteins instead of merely blocking them?

🔬 Meet PROTACs and molecular glues—innovative drugs that harness the cell's recycling machinery to destroy troublesome proteins.

📊 In multiple myeloma, a molecular-glue-based combination achieved 42 vs. 20 months of progression-free survival.

💰 With ~200 degraders in development and over $5 billion in deals, the pharmaceutical industry is betting big!

⚠️ The challenge? Avoiding destruction of healthy proteins.

🎙️ Dr RR Baliga's Podkast for the Kurious Doc

Where Curiosity Meets Clarity!

#PrecisionMedicine #Oncology #DrugDiscovery