Methylation Explained: MTHFR, B12, Folate and the Genes Almost Nobody Checks

Your blood tests come back "normal", but you don't feel normal.

You wake at 3am with your mind racing, your hands and feet are always cold, the fog won't lift and your energy has gone. In this solo episode I unpack methylation, one of the most important systems in your body and one almost nobody is testing for. In this episode: - What methylation actually does, and why SAMe and homocysteine matter so much -

The gene team behind it: MTHFR, MTR, MTRR, TCN2, FUT2, DHFR, COMT, PEMT, HNMT, CYP1B1, NOS3, CBS and BHMT - Who is most at risk, including medications and lifestyle factors that quietly drain B12 and folate - What high homocysteine means for your bones, heart and blood vessels, brain, mood, hormones and histamine -

Why I don't use folic acid, and what I use instead: methylfolate, folinic acid and the right forms of B12 - The methyl trap, and why folate and B12 always need fixing together -

Why taking SAMe on its own isn't the fix - The supporting cast: riboflavin, B6, choline, TMG and omega-3 -

How to test properly: homocysteine, active B12, folate, MMA and MCV If you're pregnant or planning a pregnancy, don't change your folate on your own.

Get properly assessed first.

Want to know what your own methylation genes are doing?

My DNA Blueprint Package covers methylation, COMT, PEMT, your oestrogen genes and much more, with a personalised plan and a one-on-one consult with me. https://lisatamati.com/dna

Watch the full video on YouTube: search "Lisa Tamati methylation" More episodes: https://www.lisatamati.com/ptl-podcast/

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This episode is for education only and isn't individual medical advice.