Ep 272: Is science truly explanatory?

A reaction to  @CosmicSkeptic  and  @SabineHossenfelder  discussing the nature, or even possibility of, genuine scientific explanation in this video: https://youtu.be/KWBm0_1QBDs?si=3JwIDGAtumO3mfBz Which of them is correct? Or are they both wrong? What counts as an explanation? What counts as a scientific explanation? What counts as a good scientific explanation? And is Alex right that science, in some ultimate sense, really only ever describes things?