
← From First Principles16 okt · 1 u 59 min
Nobel Prize 2026: The Science Gets Stranger
<p>Can light restore aspects of sight? Can recalling a cold experience change an animal's metabolism? And what can ghost particles and mirror-image molecules tell us about the universe?</p><p>Lester Nare and Krishna Choudhary follow up on our 2026 Nobel Prize episodes with research building on optogenetics, IceCube and molecular handedness. We unpack an early human vision-restoration trial, cold-memory experiments in mice, cosmic neutrino flavors, and a tiny electrical sensor for distinguishing left- and right-handed amino acids.</p><p>Plus: how the Nobels work, our follow-up on the Nobel chemistry illustration, a brief look at neutrino Earth tomography, and why fundamental research matters. Which discovery would you like us to explore next?</p><p>CHAPTERS<br />00:00 Cold open: memory, neutrinos and mirror molecules<br />00:28 Hello Internet and how the Nobels work<br />04:32 Optogenetics recap<br />10:23 Restoring aspects of vision<br />25:43 Controlling movement in worms<br />29:31 Cold memories and metabolism<br />41:07 Memory, trauma and ethical questions<br />45:44 FFP housekeeping<br />48:17 IceCube recap<br />56:23 Measuring cosmic neutrino flavors<br />1:10:30 A brief look at neutrino Earth tomography<br />1:12:20 Why fundamental physics matters<br />1:26:58 Chemistry and molecular handedness<br />1:29:08 Correcting the Nobel illustration<br />1:39:30 Measuring chirality in tiny samples<br />1:46:42 Testing the sensor on meteorite and desert samples<br />1:51:22 Why these questions matter<br />1:57:20 Closing thoughts and signoff</p><p>RESEARCH & FURTHER READING<br />Optogenetic therapy for visual function (NEJM, 2026):<br />https://doi.org/10.1056/NEJMoa2602215</p><p>Cold memories and thermoregulation (Nature, 2025):<br />https://doi.org/10.1038/s41586-025-08902-6</p><p>Three-flavor composition of cosmic neutrinos (PRL, 2026):<br />https://doi.org/10.1103/vntd-m133</p><p>Chiral discrimination in meteorite and desert soil extracts (Nature Communications, 2026):<br />https://doi.org/10.1038/s41467-026-77947-6</p><p>Further reading, briefly mentioned: neutrino Earth tomography (preprint):<br />https://arxiv.org/abs/2607.02644</p><p>EDITORIAL NOTES<br />The vision trial was small and exploratory. The cold-memory findings discussed are from mice.</p><p>On-screen clarifications:<br />16:53 Both eyes were profoundly visually impaired; the worse-seeing eye was treated.<br />19:57 The untreated eye was patched during testing, not a normal-vision contro